HCSGD entry for PLXNA3

1. General information

Official gene symbolPLXNA3
Entrez ID55558
Gene full nameplexin A3
Other gene symbols6.3 HSSEXGENE PLEXIN-A3 PLXN3 PLXN4 SEX XAP-6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002116Semaphorin receptor complexTAScellular_component
GO:0004888Transmembrane signaling receptor activityNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0016020MembraneTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0017154Semaphorin receptor activityIEAmolecular_function
GO:0021766Hippocampus developmentIEAbiological_process
GO:0021860Pyramidal neuron developmentIEAbiological_process
GO:0048843Negative regulation of axon extension involved in axon guidanceIEAbiological_process
GO:0050919Negative chemotaxisIEAbiological_process
GO:0051495Positive regulation of cytoskeleton organizationIEAbiological_process
GO:0071526Semaphorin-plexin signaling pathwayNASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02737712090.96878844270.38388109691.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1071889938
GSE13712_SHEARUp0.2953818646
GSE13712_STATICUp0.1425372183
GSE19018Up0.1109196024
GSE19899_A1Up0.0456937037
GSE19899_A2Up0.1674166323
PubMed_21979375_A1Up0.2316028245
PubMed_21979375_A2Up0.2485565931
GSE35957Up0.0282264265
GSE36640Up0.9807884375
GSE54402Up0.0951106934
GSE9593Up0.4096346506
GSE43922Up0.1135570291
GSE24585Up0.4689387752
GSE37065Down-0.1108666387
GSE28863_A1Up0.4201600311
GSE28863_A2Up0.6167730923
GSE28863_A3Up0.0117497225
GSE28863_A4Down-0.1419513946
GSE48662Up0.6826898286

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018079MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.