HCSGD entry for PLXNA3

1. General information

Official gene symbolPLXNA3
Entrez ID55558
Gene full nameplexin A3
Other gene symbols6.3 HSSEXGENE PLEXIN-A3 PLXN3 PLXN4 SEX XAP-6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002116Semaphorin receptor complexTAScellular_component
GO:0004888Transmembrane signaling receptor activityNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0016020MembraneTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0017154Semaphorin receptor activityIEAmolecular_function
GO:0021766Hippocampus developmentIEAbiological_process
GO:0021860Pyramidal neuron developmentIEAbiological_process
GO:0048843Negative regulation of axon extension involved in axon guidanceIEAbiological_process
GO:0050919Negative chemotaxisIEAbiological_process
GO:0051495Positive regulation of cytoskeleton organizationIEAbiological_process
GO:0071526Semaphorin-plexin signaling pathwayNASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02737712090.96878844270.38388109691.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1071889938
GSE13712_SHEARUp0.2953818646
GSE13712_STATICUp0.1425372183
GSE19018Up0.1109196024
GSE19899_A1Up0.0456937037
GSE19899_A2Up0.1674166323
PubMed_21979375_A1Up0.2316028245
PubMed_21979375_A2Up0.2485565931
GSE35957Up0.0282264265
GSE36640Up0.9807884375
GSE54402Up0.0951106934
GSE9593Up0.4096346506
GSE43922Up0.1135570291
GSE24585Up0.4689387752
GSE37065Down-0.1108666387
GSE28863_A1Up0.4201600311
GSE28863_A2Up0.6167730923
GSE28863_A3Up0.0117497225
GSE28863_A4Down-0.1419513946
GSE48662Up0.6826898286

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018079MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.