HCSGD entry for OVOL2


1. General information

Official gene symbolOVOL2
Entrez ID58495
Gene full nameovo-like 2 (Drosophila)
Other gene symbolsEUROIMAGE566589 ZNF339
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000981Sequence-specific DNA binding RNA polymerase II transcription factor activityIBAmolecular_function
GO:0001525AngiogenesisIEAbiological_process
GO:0001755Neural crest cell migrationIEAbiological_process
GO:0001842Neural fold formationIEAbiological_process
GO:0001947Heart loopingIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0005634NucleusIBA ICcellular_component
GO:0006357Regulation of transcription from RNA polymerase II promoterIBAbiological_process
GO:0006366Transcription from RNA polymerase II promoterIBAbiological_process
GO:0008285Negative regulation of cell proliferationIEAbiological_process
GO:0009953Dorsal/ventral pattern formationIEAbiological_process
GO:0010837Regulation of keratinocyte proliferationIEA IMPbiological_process
GO:0010944Negative regulation of transcription by competitive promoter bindingIDAbiological_process
GO:0044212Transcription regulatory region DNA bindingIDAmolecular_function
GO:0045617Negative regulation of keratinocyte differentiationIMPbiological_process
GO:0045746Negative regulation of Notch signaling pathwayIDAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIEAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048557Embryonic digestive tract morphogenesisIEAbiological_process
GO:0051726Regulation of cell cycleIMPbiological_process
GO:0060214Endocardium formationIEAbiological_process
GO:0060347Heart trabecula formationIEAbiological_process
GO:0060716Labyrinthine layer blood vessel developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.38769362490.91203466430.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0519475850
GSE13712_SHEARDown-0.0348823128
GSE13712_STATICUp0.0437451960
GSE19018Down-0.0271962620
GSE19899_A1Up0.1416004110
GSE19899_A2Down-0.0035628003
PubMed_21979375_A1Up0.0137440239
PubMed_21979375_A2Up0.0444358543
GSE35957Up0.1833344108
GSE36640Down-0.0216973565
GSE54402Up0.0938565782
GSE9593Down-0.0505812868
GSE43922Up0.0332183598
GSE24585Up0.0527371057
GSE37065Down-0.0402686440
GSE28863_A1Up0.2767320131
GSE28863_A2Up0.0671057432
GSE28863_A3Up0.0626486305
GSE28863_A4Up0.2170650386
GSE48662Down-0.0294250787

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.