HCSGD entry for OVOL2

1. General information

Official gene symbolOVOL2
Entrez ID58495
Gene full nameovo-like 2 (Drosophila)
Other gene symbolsEUROIMAGE566589 ZNF339
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000981Sequence-specific DNA binding RNA polymerase II transcription factor activityIBAmolecular_function
GO:0001525AngiogenesisIEAbiological_process
GO:0001755Neural crest cell migrationIEAbiological_process
GO:0001842Neural fold formationIEAbiological_process
GO:0001947Heart loopingIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0005634NucleusIBA ICcellular_component
GO:0006357Regulation of transcription from RNA polymerase II promoterIBAbiological_process
GO:0006366Transcription from RNA polymerase II promoterIBAbiological_process
GO:0008285Negative regulation of cell proliferationIEAbiological_process
GO:0009953Dorsal/ventral pattern formationIEAbiological_process
GO:0010837Regulation of keratinocyte proliferationIEA IMPbiological_process
GO:0010944Negative regulation of transcription by competitive promoter bindingIDAbiological_process
GO:0044212Transcription regulatory region DNA bindingIDAmolecular_function
GO:0045617Negative regulation of keratinocyte differentiationIMPbiological_process
GO:0045746Negative regulation of Notch signaling pathwayIDAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIEAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048557Embryonic digestive tract morphogenesisIEAbiological_process
GO:0051726Regulation of cell cycleIMPbiological_process
GO:0060214Endocardium formationIEAbiological_process
GO:0060347Heart trabecula formationIEAbiological_process
GO:0060716Labyrinthine layer blood vessel developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.38769362490.91203466430.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0519475850
GSE13712_SHEARDown-0.0348823128
GSE13712_STATICUp0.0437451960
GSE19018Down-0.0271962620
GSE19899_A1Up0.1416004110
GSE19899_A2Down-0.0035628003
PubMed_21979375_A1Up0.0137440239
PubMed_21979375_A2Up0.0444358543
GSE35957Up0.1833344108
GSE36640Down-0.0216973565
GSE54402Up0.0938565782
GSE9593Down-0.0505812868
GSE43922Up0.0332183598
GSE24585Up0.0527371057
GSE37065Down-0.0402686440
GSE28863_A1Up0.2767320131
GSE28863_A2Up0.0671057432
GSE28863_A3Up0.0626486305
GSE28863_A4Up0.2170650386
GSE48662Down-0.0294250787

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.