HCSGD entry for TMEM109


1. General information

Official gene symbolTMEM109
Entrez ID79073
Gene full nametransmembrane protein 109
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003674Molecular_functionNDmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005640Nuclear outer membraneIEAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0031965Nuclear membraneIDAcellular_component
GO:0033017Sarcoplasmic reticulum membraneIEAcellular_component
GO:0042771Intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorIEAbiological_process
GO:0060548Negative regulation of cell deathIMPbiological_process
GO:0071480Cellular response to gamma radiationIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.71501543630.01709382240.99999024730.2562223804

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1075756993
GSE13712_SHEARUp0.0284254645
GSE13712_STATICDown-0.1698829066
GSE19018Up0.2632246244
GSE19899_A1Down-1.2941856364
GSE19899_A2Down-1.1926332346
PubMed_21979375_A1Down-1.3436218806
PubMed_21979375_A2Down-1.1430311795
GSE35957Down-0.4544783540
GSE36640Down-0.2542218010
GSE54402Down-0.6908149413
GSE9593Up0.1693064246
GSE43922Down-0.5714965776
GSE24585Down-0.4709865004
GSE37065Up0.1430688886
GSE28863_A1Up0.5578393004
GSE28863_A2Up0.5468552876
GSE28863_A3Down-0.0490746314
GSE28863_A4Up0.0856100127
GSE48662Up0.3694747217

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT001407pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-124-3pMIMAT0000422MIRT004883MicroarrayFunctional MTI (Weak)15685193
hsa-miR-124-3pMIMAT0000422MIRT004883MicroarrayFunctional MTI (Weak)18668037
hsa-miR-130b-3pMIMAT0000691MIRT020256SequencingFunctional MTI (Weak)20371350
hsa-miR-34a-5pMIMAT0000255MIRT025524ProteomicsFunctional MTI (Weak)21566225
hsa-miR-342-5pMIMAT0004694MIRT038221CLASHFunctional MTI (Weak)23622248
hsa-miR-421MIMAT0003339MIRT039449CLASHFunctional MTI (Weak)23622248
hsa-miR-18a-3pMIMAT0002891MIRT040811CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.