HCSGD entry for TMEM109
1. General information
| Official gene symbol | TMEM109 |
|---|---|
| Entrez ID | 79073 |
| Gene full name | transmembrane protein 109 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005640 | Nuclear outer membrane | IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0031965 | Nuclear membrane | IDA | cellular_component |
| GO:0033017 | Sarcoplasmic reticulum membrane | IEA | cellular_component |
| GO:0042771 | Intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | IEA | biological_process |
| GO:0060548 | Negative regulation of cell death | IMP | biological_process |
| GO:0071480 | Cellular response to gamma radiation | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7150154363 | 0.0170938224 | 0.9999902473 | 0.2562223804 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1075756993 |
| GSE13712_SHEAR | Up | 0.0284254645 |
| GSE13712_STATIC | Down | -0.1698829066 |
| GSE19018 | Up | 0.2632246244 |
| GSE19899_A1 | Down | -1.2941856364 |
| GSE19899_A2 | Down | -1.1926332346 |
| PubMed_21979375_A1 | Down | -1.3436218806 |
| PubMed_21979375_A2 | Down | -1.1430311795 |
| GSE35957 | Down | -0.4544783540 |
| GSE36640 | Down | -0.2542218010 |
| GSE54402 | Down | -0.6908149413 |
| GSE9593 | Up | 0.1693064246 |
| GSE43922 | Down | -0.5714965776 |
| GSE24585 | Down | -0.4709865004 |
| GSE37065 | Up | 0.1430688886 |
| GSE28863_A1 | Up | 0.5578393004 |
| GSE28863_A2 | Up | 0.5468552876 |
| GSE28863_A3 | Down | -0.0490746314 |
| GSE28863_A4 | Up | 0.0856100127 |
| GSE48662 | Up | 0.3694747217 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT001407 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT004883 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT004883 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020256 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025524 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-342-5p | MIMAT0004694 | MIRT038221 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-421 | MIMAT0003339 | MIRT039449 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040811 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
