HCSGD entry for SUPT3H

1. General information

Official gene symbolSUPT3H
Entrez ID8464
Gene full namesuppressor of Ty 3 homolog (S. cerevisiae)
Other gene symbolsSPT3 SPT3L
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003713Transcription coactivator activityIDAmolecular_function
GO:0004402Histone acetyltransferase activityIDAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006355Regulation of transcription, DNA-templatedNASbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0006366Transcription from RNA polymerase II promoterIEAbiological_process
GO:0016578Histone deubiquitinationIDAbiological_process
GO:0030914STAGA complexIDAcellular_component
GO:0033276Transcription factor TFTC complexIDAcellular_component
GO:0043966Histone H3 acetylationIDAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedNASbiological_process
GO:0046982Protein heterodimerization activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.87346878920.30374690930.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0663074150
GSE13712_SHEARDown-0.1521177463
GSE13712_STATICDown-0.2135355662
GSE19018Up0.1239304668
GSE19899_A1Down-0.0001024542
GSE19899_A2Down-0.2548755894
PubMed_21979375_A1Up0.4995304304
PubMed_21979375_A2Up0.0762408779
GSE35957Up0.0050468305
GSE36640Down-0.2100774459
GSE54402Up0.0723371434
GSE9593Up0.1649879589
GSE43922Down-0.2268622852
GSE24585Up0.0468758697
GSE37065Up0.0151792565
GSE28863_A1Down-0.1403816746
GSE28863_A2Down-0.0415813883
GSE28863_A3Down-0.2119167616
GSE28863_A4Down-0.3457390796
GSE48662Down-0.0691749787

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029827MicroarrayFunctional MTI (Weak)19088304
hsa-miR-15b-5pMIMAT0000417MIRT046510CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.