HCSGD entry for SUPT3H

1. General information

Official gene symbolSUPT3H
Entrez ID8464
Gene full namesuppressor of Ty 3 homolog (S. cerevisiae)
Other gene symbolsSPT3 SPT3L
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003713Transcription coactivator activityIDAmolecular_function
GO:0004402Histone acetyltransferase activityIDAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006355Regulation of transcription, DNA-templatedNASbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0006366Transcription from RNA polymerase II promoterIEAbiological_process
GO:0016578Histone deubiquitinationIDAbiological_process
GO:0030914STAGA complexIDAcellular_component
GO:0033276Transcription factor TFTC complexIDAcellular_component
GO:0043966Histone H3 acetylationIDAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedNASbiological_process
GO:0046982Protein heterodimerization activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.87346878920.30374690930.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0663074150
GSE13712_SHEARDown-0.1521177463
GSE13712_STATICDown-0.2135355662
GSE19018Up0.1239304668
GSE19899_A1Down-0.0001024542
GSE19899_A2Down-0.2548755894
PubMed_21979375_A1Up0.4995304304
PubMed_21979375_A2Up0.0762408779
GSE35957Up0.0050468305
GSE36640Down-0.2100774459
GSE54402Up0.0723371434
GSE9593Up0.1649879589
GSE43922Down-0.2268622852
GSE24585Up0.0468758697
GSE37065Up0.0151792565
GSE28863_A1Down-0.1403816746
GSE28863_A2Down-0.0415813883
GSE28863_A3Down-0.2119167616
GSE28863_A4Down-0.3457390796
GSE48662Down-0.0691749787

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029827MicroarrayFunctional MTI (Weak)19088304
hsa-miR-15b-5pMIMAT0000417MIRT046510CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.