HCSGD entry for KLK1

1. General information

Official gene symbolKLK1
Entrez ID3816
Gene full namekallikrein 1
Other gene symbolsKLKR Klk6 hK1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004252Serine-type endopeptidase activityIEA NASmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0006508ProteolysisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82075179510.24314933320.99999024730.9492633640

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1594752282
GSE13712_SHEARDown-0.1867606013
GSE13712_STATICDown-0.0468358761
GSE19018Down-0.0220627996
GSE19899_A1Down-0.0205490834
GSE19899_A2Up0.1767552459
PubMed_21979375_A1Down-0.2454739652
PubMed_21979375_A2Down-0.2172011624
GSE35957Up0.0280180529
GSE36640Down-0.0147872287
GSE54402Down-0.1053145228
GSE9593Up0.0552269039
GSE43922Up0.1486110772
GSE24585Up0.1194109913
GSE37065Up0.0607230699
GSE28863_A1Down-0.4760434967
GSE28863_A2Down-0.3846166366
GSE28863_A3Up0.1399487888
GSE28863_A4Up0.2668338593
GSE48662Up0.0121427408

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

AprotininDB06692 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-224-5pMIMAT0000281NAhsa-miR-224{ELISA}{overexpression}20180642
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.